Blog Archives

Volume 69 (1)

Stefan Kuzmanovski, Emilija Valjakova – Bajraktarova
Air abrasion or silicatization – optimal conditioning method for zirconium dioxide prosthetic restorations due to the bonding of ceramic orthodontic brackets [PDF]
Early on-line  6 November 2023

Zoya Dzhakova, Diana Karcheva-Bahchevanska, Stanislava Ivanova
Lepidium meyenii biological activity and future perspectives [PDF]
Early on-line  22 August 2023

Velislava Todorova, Diana Karcheva-Bahchevanska, Stanislava Ivanova
GC-MS analysis of cholesterol lowering dietary supplements [PDF]
Early on-line  22 August 2023

Veronika Popovska Jakimovska, Ana Atanasova, Filip Gogu, Maja Stevanoska, Emilija Arsovska Popovska, Packa Antovska, Suzana Trajkovic Jolevska, Jasmina Tonic Ribarska
Analytical Quality by Design approach in development and optimization of HPLC method for assay of angiotensin – converting enzyme inhibitor in tablets [PDF]
Early on-line  22 August 2023

Andrea Alagjozovska, Milena Dobrkovikj Shotarovska, Maja Mindoseva, Stefan Petrovski, Gordana Mitrovska, Sanja Despotovska, Ornela Kuzmanovska, Elizabeta Karadzinska, Olivera Paneva
Workflow for investigation of Out of Specification results in physico-chemical laboratory in Alkaloid [PDF]

Early online 24 September 2023

Aleksandra Chakarjanevska, Marika Bogoevska Nikolovska, Mirsada Dervisevic Andonov,
Irena Slaveska Spirevska, Marija Karapandzova, Suzana Trajkovic Jolevska, Jasmina Tonic Ribarska
Stability study of Fluconazole capsules with Bracketing Design  [PDF]
Early on-line  31 December 2023

Marija Grozdanoska Kostadinovska, Sacha Manuel, Nena Velevska, Packa Antovska, Jelena Lazova, Jasmina Tonic Ribarska, Rumenka Petkovska, Suzana Trajkovic Jolevska
Development and validation of an in vitro release test and use of Strat-M synthetic membrane as a predictor for the in vitro permeation test of topical gel formulations [PDF]
Early on-line  31 December 2023

Martina Miloshevska, Irena Slaveska Spirevska, Natalija Nakov, Gjoshe Stefkov, Aneta Dimitrovska, Jelena Acevska arija Grozdanoska Kostadinovska, Sacha Manuel, Nena Velevska, Packa Antovska,
Water content determination in different varieties of Cannabis flowers [PDF]
Early on-line  31 December 2023

Volume 68 (2)

Donika Hoxha, Biljana Bauer, Gjoshe Stefkov, Gresa Hoxha
Phenolic phytochemicals for treatment of Alzheimer’s condition – a review [PDF]
Early on-line  15 May 2023

Mirela Ristovska-Mladenovska, Marija Darkovska Serafimovska, Marija Mitevska, Tijana Serafimovska, Zlatko Keskovski, Sasho Stefanoski, Aneta Dimitrovska
Development and validation of GC/MS method for determination of residual ethanol in Cannabis extract  [PDF]
Early on-line  11 December 2022

Ivana Cvetkovikj Karanfilova, Veronika Stoilkovska Gjorgievska, Gjoshe Stefkov, Marija Karapandzova, Ana Trajkovska, Iskra Davkova, Jelena Acevska, Svetlana Kulevanova, Katerina Brezovska
DAB method transfer for potency of cannabinoids in dry cannabis flower [PDF]
Early on-line  21 December 2022

Iva Antova, Mario Ignjatovikj, Packa Antovska, Jelena Lazova, Stojne Tanevska, Marina Petreska, Jasmina Tonic Ribarska, Suzana Trajkovic Jolevska
A validated and discriminatory in vitro release test for evaluation of marketed Clotrimazole cream formulations [PDF]
Early on-line  21 December 2022

Shkendije Imeri, Snezana Zaharieva, Gordana Majnova, Suzana Angelova, Jelena Acevska, Katerina Brezovska, Vasil Karchev, Aneta Dimitrovska
Overview of the compendial methods for quantitative determination of glucose in solutions for intravenous infusion [PDF]
Early on-line  3 April 2023

Gordana Dameska, Biljana Bauer
The quality of drinking water in the Prilep region supplied by the Studenchica Regional Water Supply System and PHI General Hospital Prilep  [PDF]
Early on-line  28 December 2022

Emilija Serafimova Mijalova, Elena Tortevska Danilov, Vasil Pendevski1, Zoran Zhivikj, Lidija Petrushevska-Tozi, Tanja Petreska Ivanovska
Concentration of heavy metals in spring waters of Kochani and their impact on human health [PDF]
Early on-line  3 April 2023

Andrea Alagjozovska, Gordana Mitrovska, Jelena Acevska 
Regulatory requirements for verification of sampling plan for solid pharmaceutical bulk product [PDF]
Early on-line  3 April 2023

Marina Mandzukovska Micevska, Gjorgi Petrusevski, Rumenka Petkovska
Risk based approach on data integrity aspects of configuring computerized system in GMP laboratory  [PDF]
Early on-line  28 December 2022

Tina Achkoska, Marijana Bozhinovska, Angela Arnaudova, Packa Antovska, Liljana Anastasova, Rumenka Petkovska
Bootstrap analysis for dissolution similarity factor f2 – bringing confidence for borderline results – a case study [PDF]
Early on-line  11 December 2022

 

 

 

 

Volume 69 (Suppl 1) – 14th CESPT

69 (Suppl 1) Full Issue [PDF]

Table of Contents [PDF]

Stefaan C. De Smedt, Kevin Braeckmans, Katrien Remaut, Félix Sauvage, Karen Peynshaert
Exploring light for advanced drug delivery & surgery in the eye [PDF]

Bojana Obradović, Jasmina Stojkovska, Ivana Banićević, Anđela Radisavljević, Marija Jovanović, Miloš Petrović, Mirjana Rajilić-Stojanović, Petar Uskoković, Dušica Stojanović, Vesna Radojević
The ExcellMater project for advancements in biomaterials and 3D in vitro culture systems for applications in pharmacy and biomedicine [PDF]

Pálma Fehér, Liza Józsa, Tünde Jurca, Annamária Pallag, Ágota Pető, Dóra Kósa, Ildikó Bácskay
Topical formulations containing Rosa Damascena for the treatment of Psoriasis [PDF]

Mahwash Mukhtar, Rita Ambrus
Macrophages as a target for drug delivery: a boon to nano-therapeutics [PDF]

Greta Camilla Magnano, Marika Quadri, Elisabetta Palazzo, Francesca Loschi, Stefano dell’Acqua, Alessandra Marconi
3D human foreskin model as an alternative method for testing topical formulations [PDF]

Dávid Sinka, Nóra Szendi, Jázmin Páll, Ildikó Bácskay
Formulation and investigation of fenugreek extract SEDDS systems [PDF]

Bence Sipos, Ildikó Csóka, Gábor Katona
In vivo brain distribution investigation of nasal polymeric and albumin-based nanocarriers [PDF]

Ljubica Mihailova, Dushko Shalabalija, Nikola Geskovski, Otmar Geiss, Sabrina Gioria, Diletta Scaccabarozzi, Andreas Zimmer, Marija Glavas Dodov
DLS and AF4-MALS/DLS as powerful techniques for in vitro evaluation of nanoliposomes stability in biorelevant medium [PDF]

Liza Józsa, Ildikó Bácskay, Pálma Fehér
Novel self-nanoemulsifying drug delivery systems containing Curcumin for topical drug delivery [PDF]

Christina Glader, Ramona Jeitler, Yan Wang, Carolin Tetyczka, Manuel Zettl, Johannes Khinast, Manon Rossano, Steve Mesite, Matthias Lübbert, Eva Roblegg
Establishment of a continuous inline-monitored nano-production line using the Microfluidizer® technology for the fabrication of safe lipid-based nanoparticles [PDF]

Josif Kachurov, Zorica Kachurov
Comparative review of self-nanoemulsifying drug delivery systems with Rosuvastatin [PDF]

Zora Rukavina, Maja Šegvić Klarić, Željka Vanić
Liposomes-in-chitosan hydrogel improves efficacy of azithromycin against methicillin-resistant Staphylococcus aureus [PDF]

Barbara Sterle Zorec, Rok Dreu
Evaluation of 2D printing cartridges containing spray-dried drug-polymer particles [PDF]

Kristina Vlahovic, Miléna Lengyel, Nikolett Kállai-Szabó, Bence Borbás, István Antal
Spray drying process parameter optimization for co-processed materials [PDF]

Olga Napierała, Loredana Marin, Jarosław Pieczuro, Janina Lulek, Marcin Skotnicki
Thermal analysis of a co-amorphous olanzapine-tryptophan system obtained by a spray drying process [PDF]

Acelya Ece Ugurlu, Ugur Karagoz
Preparation of the Ascorbic acid and Ferulic acid loaded niosomes [PDF]

Piotr Gadziński, Tomasz Osmałek, Anna Froelich, Barbara Jadach
Ionotropic gelation and chemical crosslinking as tools to obtain matrix capsules with mesalazine [PDF]

Olariu Ioana Viorica, Muţ Ana Maria, Vlaia Vicenţiu, Coneac Georgeta, Vlaia Lavinia
Preliminary investigation of the phase behavior of systems containing black cumin seed oil, nonionic surfactants and water [PDF]

Feria Hasanpour, Rita Ambrus, Martin Cseh, Zsolt Geratovszky, Szilvia Berkó
Development of Lidocaine-containing NLCs combined with 3D printed solid microneedle [PDF]

Martin Cseh, Gábor Katona, Ildikó Csóka
Influence of needle geometry on mechanical properties of 3D printed microneedle arrays [PDF]

Maria Gioia Fabiano, Maria Valeria Giuli, Patrizia Nadia Hanieh, Jacopo Forte, Federica Rinaldi, Carlotta Marianecci, Saula Checquolo, Maria Carafa
pH-sensitive niosomal ATRA delivery as a promising approach to inhibit Pin1 in High-Grade Serous Ovarian Cancer [PDF]

Gábor Katona, Ildikó Csóka, Bence Sipos, Ilona Gróf, Mária A. Deli, György Tibor Balogh
Investigation of drug release and permeability behavior of different species-specific serum albumin nanoparticles [PDF]

Boglárka Szalai, Orsolya Jójárt-Laczkovich, Mária Budai-Szűcs
In situ gelling mucoadhesive eye drops: evaluation of physicochemical properties, in vitro dissolution and transcorneal permeability [PDF]

Sabina Keser, Gordana Maravić Vlahoviček, Maja Šegvić Klarić, Željka Vanić
In vitro antimicrobial testing of ciprofloxacin-loaded vesicular phospholipid gels [PDF]

Ana Ćirić, Ljiljana Đekić
The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers [PDF]

Jelena Đoković, Bojan Marković, Dishary Sharmin, James M Cook, Miroslav Savić, Snežana Savić
Preformulation and development of preliminary nanoemulsion carrier for patent protected compound GL-II-73 [PDF]

Luca Éva Uhljar, Ildikó Csóka, Rita Ambrus
Electrospun nanofibers as potential medical devices:Short review from a regulatory perspective [PDF]

Sandra Miočić, Kristina Ferderber, Marjana Dȕrrigl, Biserka Cetina-Čižmek, Jelena Filipović-Grčić
Azelaic acid nanosuspensions stabilised by chitosan and hydroxypropyl methylcellulose [PDF]

Tetiana Kolisnyk, Valentyn Mohylyuk, Gavin P. Andrews
Drug-polymer miscibility and interaction study as a preliminary step in amorphous solid dispersion development: Comparison of theoretical and experimental data [PDF]

Asja Fajtović, Marija Smolić, Laura Nižić Nodilo
Development of sprayable Carbopol gel for dermal melatonin delivery [PDF]

Josip Ljubica, Bisera Jurišić Dukovski, Iva Krtalić, Ivan Sušanj, Ivan Pepić, Jasmina Lovrić
Ophthalmic nanoemulsion with loteprednol etabonate – preformulation parameters for a highly loaded formulation [PDF]

Josip Ljubica, Bisera Jurišić Dukovski, Drago Špoljarić, Iva Krtalić, Ivan Sušanj, Anita Hafner, Jasmina Lovrić
Loteprednol etabonate-loaded nanoemulsions for the treatment of dry eye disease: quality by design approach [PDF]

Ayse Nur Buke, Muge Kilicarslan
Investigation of the effects of stirring rate and surfactant concentration on in vitro characterization of Hypericum perforatum extract loaded polycaprolactone nanoparticles [PDF]

Gordana Damjanovska, Ljuba Karanakov, Katerina Zafirova Georgievska
Nanomedicines and off patent follow-on medicines (nanosimilars) EMA regulatory procedures overview [PDF]

Meryem Kocas, Marija Glavas Dodov, Tansel Comoglu
Development and characterization of Ivermectin loaded liposomes prepared by lipid film hydration and ethanol injection method [PDF]

Enkelejda Goci, Entela Haloci, Antonio Di Stefano, Annalisa Chiavaroli, Paola Angelini, Ajkuna Miha, Ivana Cacciatore, Lisa Marinelli
In vitro release study of Capsaicin carbopol formulation [PDF]

Uğur Karagöz
Novel niosome formulation design for gene delivery [PDF]

Nadica Vanova Nakjinova, Nikola Jovanovikj, Maja Simonoska Crcarevska, Nikola Geskovski, Lina Livrinska, Kristina Mladenovska
Effect of phospholipid-polymer conjugate on physical properties of Rosuvastatin/Ezetimibe loaded lipid-polymer hybrid nanoparticles [PDF]

Nadica Vanova Nakjinova, Nikola Jovanovikj, Maja Simonoska Crcarevska, Lina Livrinska, Kristina Mladenovska
DSPE-PEG-PLGA nanoparticles as carriers of fixed dose drug combination; effect of polymer type and concentration on their physical characteristics [PDF]

Črt Dragar, Robert Roškar, Petra Kocbek
The drug incorporation affects the properties of hydrophilic nanofibers [PDF]

Josip Ljubica, Črt Dragar, Jasmina Lovrić, Petra Kocbek
Preparation of dried nanoemulsion formulation by electrospinning [PDF]

Filip Gorachinov, Daniel Velichkovski, Maja Simonoska Crcarevska, Nikola Geskovski, Marija Glavas Dodov, Katerina Goracinova
Time dependent size control of sodium hydroxide catalyzed sol-gel synthesized silica nanoparticles modified with organosilane molecules by post-grafting [PDF]

Ayca Gungor Ak, Aysegul Karatas
Determination of antioxidant activity of different drug delivery systems loaded with BER on the liver [PDF]

Aslihan Hilal Algan, Aysegul Karatas
Preparation and characterization of Quercetin loaded polymeric nanoparticles [PDF]

Ildikó Bácskay, Dániel Nemes, Ádám Haimhoffer, Liza Józsa, Ágota Pető, Dóra Kósa, Zoltán Ujhelyi, Pálma Fehér, Gábor Vasvári
The importance of collaboration between academia and industry in pharmaceutical R&D [PDF]

Małgorzata Sznitowska, Marzena Jamrógiewicz, Bartosz Maciejewski, Barbara Mikolaszek, Justyna Strankowska, Krystyna Pieńkowska, Joanna Dłabiszewska, Sandra Dybowska, Damian Rosłonowski
Dermal acrylic and silicone patches – the effect of liquid additives [PDF]

Ewelina Baran, Artur Birczyński, Przemysław Dorożyński, Piotr Kulinowski
Pharmaceutical dosage forms by Vat Polymerization – from additive manufacturing to functional properties and formulation understanding [PDF]

Zsuzsa Czomba, István Budai, Monika Béresova, Ildikó Bácskay, Ferenc Fenyvesi, Ádám Haimhoffer
Develop gastro-retentive dosage forms by innovative hot, melt technics [PDF]

Elizabeta Atanaskova, Marina Chachorovska, Natasha Anevska Stojanovska, Gjorgji Petrushevski, Nikola Geshkovski
MVA model development for quantification of API in solid state using vibrational spectroscopy [PDF]

Ivana Vasiljević, Erna Turković, Jelena Parojčić
Data mining implementation in multiparticulate unit systems characterization [PDF]

Kristiine Roostar, Karin Lombiots, Oleh Koshovyi, Jyrki Heinämäki,Niklas Sandler-Topelius, Urve Paaver
Application of semi-solid extrusion (SSE) 3D printing for generating customized propranolol-loaded oral drug delivery systems [PDF]

Jasmina Stojkovska, Jelena Petrović, Milena Milivojević, Milena Stevanović, Miodrag Dragoj, Milica Pešić, Radmila Janković, Bojana Obradović
Tumor mimetic platform for clinically relevant novel drug screening [PDF]

Ayse Nur Buke, Muge Kilicarslan, Osama Ali Hindy, Pinar Yilgor Huri
The effect of plasticizers and crosslinking on the printability, structural properties and release behaviour of boric acid-loaded chitosan films prepared by 3D printing [PDF]

Sıla Gülbağ Pinar, Gizem Tezel, Hakan Eroğlu, Nevin Çelebi
Preformulation study of a new dosage form for Parkinson’s disease: Orally disintegrating film of ropinirole hydrochloride [PDF]

Erna Turković, Ivana Vasiljević, Jelena Parojčić
Application of the Gradient boosted tree approach for thin film classification based on disintegration time [PDF]

Dániel Nemes, Ildikó Bácskay
Antimicrobial and biocompatibility study of sorbate derivates [PDF]

Teja Brezovar, Rok Dreu
Assessment of pellet mixture segregation during machine capsule filling [PDF]

Sevgi Tektaş, Nilüfer Yüksel, Tuğrul Mert Serim, Ayşe Nurten Ozdemir
Design and in vitro characterization of in situ forming prolonged release implant formulations of a narcotic antagonist drug [PDF]

Marta Szekalska, Katarzyna Olechno, Katarzyna Winnicka
Preliminary evaluation of alginate/pectin buccal films with posaconazole prepared by solvent casting technique [PDF]

Ágota Pető, Dóra Kósa, Ádám Haimhoffer , Dániel Nemes,Annamária Pallag, Tünde Jurca, Ildikó Bácskay
Topical formulation of lyophilized P. coronarius leaf and flower extracts, antimicrobial assessment of the plant [PDF]

Anđela Dragićević, Dragana Pavlović, Marija Tasić-Kostov
Hydrolates as water phase in cosmetic creams: physicochemical and in vivo assessment [PDF]

Aleksandra Krstevska, Ivana Nedekov, Maša Petrović, Svetlana Ibric, Dušica Mirković, Sandra Cvijić
In silico assessment of intestinal precipitation: Case study of a poorly soluble, weakly basic compound [PDF]

Ivana Kurćubić, Svetlana Ibrić, Jelena Djuriš
Assessment of mucoadhesive buccal tablets with propranolol hydrochloride using principal component analysis [PDF]

Marina Tihhonova, Andres Meos, Sari Airaksinen, Niklas Sandler-Topelius, Jyrki Heinämäki, Urve Paaver
Formulation and evaluation of 3D-printed prednisolone-loaded tablets intended for veterinary applications [PDF]

Ivana Adamov, Gordana Stanojević, David Kočović, Snežana Mugoša, Branka Grujić, Svetlana Ibrić
Selective laser sintering (SLS) 3D printing process: Influence of model design on the properties of zolpidem tartrate tablets [PDF]

Dušan Ilić, Maja Cvetković, Ana Žugić, Slavica Sunarić, Marija Tasić-Kostov
In vitro spironolactone permeation study: role of different alkyl polyglucoside emulsifiers and glycolic acid [PDF]

Filip Gorachinov, Katerina Tnokovska, Monika Koviloska, Ana Atanasova, Packa Antovska, Jelena Lazova, Nikola Geskovski
FT-NIR as a technique for objective measurement of film quality parameters [PDF]

Ivana Aleksić, Slobodanka Ćirin-Varađan, Teodora Glišić, Nađa Petrović, Jelena Đuriš, Jelena Parojčić
From co-processing by melt granulation towards direct compression of high ibuprofen loaded formulations [PDF]

Grozdana Leshevska, Bojan Papadinov
Digitalization in the pharmaceutical industry: Forms of digitalization with emphasis on Pharma 4.0 [PDF]

Krzysztof Wentowski, Piotr Lisiecki, Stefan Malycha
Industrial approach to Rivaroxaban-Aspirin fixed-dose combination formulation [PDF]

Aleksandra Krstevska, Jelena Đjurić, Svetlana Ibric, Sandra Cvijić
A text mining study on the utility of physiologically based pharmacokinetic/biopharmaceutics modeling (PBPK/PBBM) in formulation development [PDF]

Tamara Ivanoska, Vlado Petrushevski, Raba Renda, Ivana Klinkarova, Oja Ali Memed
Evaluation of influence of viscosity as main CQA on raft properties of alginate based anti-reflux suspension using DoE [PDF]

Mihail Aleksandrov, Olgica Gelevska, Cvetanka Stojova, Ivan Ivanov, Lence Ananieva Bozinov, Viktorija Maksimova
Cannabidiol based borderline products – from development to registration processes [PDF]

Katerina Kolevska, Marija Atanasova Lazarova, Maja Chochevska, Maja Velichkovska, Emilija Janevik-Ivanovska, Bistra Angelovska, Ana Ugrinska
Zirconium-89 labeled antibodies: general considerations towards radioisotope production and labelling strategies [PDF]

Jovana Kovačević, Nataša Đorđević-Filijović, Tijana Miletić, Mirjana Mršić, Jovan Jelić, Gordana Sarić, Aleksandar Pavlović
Application of classification trees technique in optimization of parameters of production of film-coated tablets [PDF]

Marija Atanasova Lazareva, Katerina Kolevska, Maja Chochevska, Maja Velichkovska, Filip Jolevski, Ana Ugrinska, Emilija Janevik-Ivanovska
The influence of cation-exchange cartridge on quality of [18F]NaF radiopharmaceutical [PDF]

Liljana Makraduli, Hristina Savreska Dujovska, Sanja Milosevic Krstevska, Natasa Milanovic, Ana Aksentieva, Irena Slaveska Spirovska, Filip Makraduli
Product quality review for assay and dissolution of Nimesulide tablets 100 mg [PDF]

Liljana Makraduli, Hristina Savreska Dujovska, Sanja Milosevic Krstevska, Natasa Milanovic, Vesna Tegova, Ivana Vuckovic, Elena Trajanovska Donev, Irena Slaveska Spirovska, Angela Gjurceska, Katerina Kocova, Elena Petrovska, Damjan Susleski
Cleaning validation of electronic counting machine with two different cleaning agents [PDF]

Elena-Emilia Tudoroiu, Mihaela Violeta Ghica, Cristina-Elena Dinu-Pîrvu, Lăcrămioara Popa, Adriana-Elena Tăerel, Răzvan Mihai Prisada, Mădălina Georgiana Albu Kaya, Bruno Ștefan Velescu,Valentina Anuța
Rheological and diffusion evaluation of topical gels with naproxen [PDF]

Fanni Falusi, Szilvia Berkó, Anita Kovács
Development and evaluation of stable hydrogel formulations with enhanced diclofenac sodium concentration for effective topical drug delivery [PDF]

Branka Grujić, Vesna Jelić, Nebojša Cvetković
Application of the experimental design techniques for donepezil hydrochloride orodispersible tablet formulation [PDF]

Isidora Nuneva, Biljana Angelevska, Darko Stojanov, Dejan Kuneski, Packa Antovska
The importance of compatibility studies in selection of appropriate TiО2 free non-functional film-coating for solid dosage formulation with antioxidant [PDF]

Nikola Pešić, Mirjana Krkobabić, Ivana Adamov, Branka Ivković, Svetlana Ibrić, Dušica Mirković, Đorđe Medarević
3D printing of carvedilol oral dosage forms using selective laser sintering technque [PDF]

Biljana Keleshovska; Dobrinka Dimova, Ana Pop Aceva
Comparation between fluid bed granulation and high shear mixer as a techniques of choice for achieving optimum homogeneity for low dose solid pharmaceutical dosage form [PDF]

Ana Juric Simčić, Michela Abrami, Iva Erak, Biserka Cetina Čižmek, Mario Grassi, Jelena Filipović-Grčić
The influence of chitosan on the microstructure and stability of a poly(D,L-lactide-co-glycolide)-based W/O emulsion to be processed by spray drying [PDF]

Yasmin Al-Eryain, Gabriel Stobbe, Marek Lachmann

Lubrication effect of three novel lubricants in comparison to some commonly used lubricants [PDF]

Nina Popović, Andrea Roje
Influence of Sodium hyaluronate molecular weight on critical quality attributes and filterability of solutions [PDF]

Maja Bjelošević Žiberna, Odon Planinšek, Pegi Ahlin Grabnar
The effect of excipients on oral lyophilizates quality attributes [PDF]

Mirna Perkušić, Laura Nižić Nodilo, Cvijeta Jakobušić Brala, Jasmina Lovrić, Ivan Pepić, Marie Trenkel, Regina Scherließ, Anita Hafner
Biopharmaceutical properties of chitosan-based thermogelling system for donepezil nasal delivery [PDF]

Sofija Lazarevska, Dobrinka Dimova, Kaliopa Simonovska, Lenche Ivcheska
The influence of formulation and hardness on the dissolution rate of ketoprofen in prolonged release tablets [PDF]

Djordje Medarević, Maša Čežek, Aleksandar Knežević, Nikola Pešić, Svetlana Ibrić, Zoran Maksimović
Functional characterization of microcrystalline cellulose obtained from the crop residues [PDF]

Ognjenka Rahić, Jasmina Hadžiabdić, Amina Tucak-Smajić, Merima Šahinović, Lamija Hindija, Marija Glavaš-Dodov, Edina Vranić
Effect of high-shear mixer head on optical properties and disintegration time of orodispersible films [PDF]

Aleksandar Cvetkovski, Elena Drakalska
Influence of beta-cyclodextrin on the phase transition in carbamazepine polymorphs [PDF]

Martin Gigovski, Nikola Geskovski, Maja Hadjieva Gigovska, Oja Memed, Ljubica Mihailova, Dusko Shalabalija, Teodora Taseska, Marija Glavas Dodov
Preparation and characterization of Glucomannan granules with controlled swelling properties [PDF]

Tetiana Kolisnyk, Olena Ruban
Modified-release oral delivery systems with the active ingredients of herbal origin: a mini-review [PDF]

Yuliia Maslii, Nataliia Herbina, Olha Mykhailenko, Viktoriia Hurina, Olena Ruban, Victoriya Georgiyants
Selection of the optimal extraction conditions of the polyphenolics from Lavandula angustifolia herbal raw materials [PDF]

Katerina Arsova, Oja Ali Memed, Tamara Ivanovska, Elena Cvetkovska Bogatinovska, Lina Livrinska, Dusko Shalabalija, Maja Simonoska Crcarevska, Nikola Geskovski, Marija Glavas Dodov, Katerina Goracinova
Fluid bed film coating of cohesive Geldart group C Ibuprofen Lysine powder [PDF]

Hristina Pislevikj, Oja Ali Memed, Tamara Ivanovska, Elena Cvetkovska Bogatinovska, Teodora Tasevska, Ljubica Mihailova, Maja Simonoska Crcarevska, Nikola Geskovski, Marija Glavas Dodov, Katerina Goracinova
Fluid bed thin film coating of ultrafine Acetaminophen particles [PDF]

Katerina Arsova Manchevska, Chedomir Cekikj
Determination the drug product quality attributes of 20% CBD solution for oral use [PDF]

Chedomir Cekikj
Post-harvest processes and methods for obtaining quality medicinal cannabis flower [PDF]

Katerina Jankulova, Iva Petrovska
Pharmaceutical waste and innovative green technologies for its treatment [PDF]

Viktor Popovski, Maja Simonoska Crcarevska, Marija Glavas Dodov, Katerina Goracinova, Nikola Geskovski
A comprehensive approach in the development and validation of a laser diffraction method for determining the particle size and size distribution of an active pharmaceutical ingredient [PDF]

Beáta-Mária Benkő, Gergő Tóth, Bence Tóth, Zoltán-István Szabó, Lajos Szente, Edina Szabó, Romána Zelkó, István Sebe
Improving the solubility and permeability of apremilast with cyclodextrin encapsulation for the development of local drug delivery systems [PDF]

Bartłomiej Milanowski, Hanna Wosicka-Frąckowiak, Stanisław Woźny, Kornelia Poniedziałek, Martyna Nyga
Physicochemical properties of acid-soluble collagen extracted from silver carp skin [PDF]

Jelena Acevska, Michel Ulmschneider, Katerina Brezovska, Aneta Dimitrovska, Bruno Spieldenner
Data analysis – quality aspects [PDF]

Anika Jahns, Andrea Schejtman, Jos Rijkx
Quality control of injectables based on ATP Bioluminescence [PDF]

Ewelina Baran, Artur Birczyński, Przemysław Dorożyński, Piotr Kulinowski
Hydrophilic polymer based oral formulations studied by NMR relaxometry and UTE MRI – towards polymer mobilization and erosion assessment [PDF]

Natalija Nakov, Liljana Anastasova, Marija Zafirova, Gabriela Petrovska-Dimitrievska, Jasmina Tonic-Ribarska, Liljana Ugrinova, Jelena Acevska, Katerina Brezovska
Experience-based insights for switching to greener chromatographic methods [PDF]

Maja Hadzieva Gigovska, Oja Ali Memed, Ivana Klinkarova, Jelena Lazova
Application of chromatography modeling technologies in development of method for related and degradation products in drug product containing two active ingredients [PDF]

Oja Ali Memed, Ivana Klinkarova, Marija Glavas Dodov
Importance of Quality by Design (QbD) approach during development of modified release film-coated tablet – objectives and challenges during implementation and preparation of dossier [PDF]

Olivera Blažeska, Natasa Anevska-Sojanovska, Jelena Lazova
GC-FID-HS method development and validation for quantitative estimation of ethanol as residual in tablets drug product from class of benzodiazepines [PDF]

Angela Arsovska, Jelena Acevska, Katerina Brezovska, Hrisanta Godzo, Aneta Dimitrovska
Risk-based assessment of the possibility for falsification during post-marketing surveillance of medicines [PDF]

Damjan Shushleski, Marjan Velkovski, Irena Slaveska Spirevska
Method suitability validation for determination of microbiological purity of Sildenafil film coated tablets 100mg [PDF]

Irena Slaveska Spirevska, Marjan Piponski, Tanja Bakovska Stoimenova, Kristina Grncharoska, Martina Miloshevska, Marijana Nikoloska, Maksim Osman Nikolov, Mimoza Sokleva Ivanova
Develompent and validation of a RP-HPLC method for simultaneous determination of Ciprofloxacin and Ornidazole in a solid dosage formulation [PDF]

Ana Grozdanoska Zdravevski, Nikola Simonovski, Nada Popstefanova
Risk reduction measures for counterfeit medicines in the supply chain [PDF]

Katerina Kochova, Irena Slaveska Spirevska, Elena Petrovska, Kristina Grncharoska, Milena Prculovska, Marijana Nikoloska, Hristina Shavrevska Dujovska, Vesna Tegova
Determination of Betamethasone residues on manufacturing equipment surfaces and PDE calculation in cleaning validation processes [PDF]

Marjan Velkovski, Damjan Shushleski, Irena Slaveska Spirevska
Method suitability validation for determination of microbiological purity of Ciprofloxacin film coated tablets [PDF]

Bartłomiej Milanowski, Mateusz Kuprianowicz
Application of a novel Revolver apparatus for biorelevant dissolution test of ropinirole sustained release tablets [PDF]

Jindra Valentová, Andrea Baránková, Desana Matušová
In vitro transdermal delivery and skin metabolism of salidroside from Rhodiola rosea extract [PDF]

Kristina Shutevska, Ana Marija Bajatovska, Zoran Zivikj, Liljana Anastasova, Tanja Petreska Ivanovska, Nikola Geskovski
PCA based screening for melamine adulteration in supplements for sport nutrition using vibrational spectroscopy tools [PDF]

Bisera Jurišić Dukovski, Josip Ljubica, Petra Kocbek, Luka Bočkor, Ivan Pepić, Anita Hafner, Jasmina Lovrić
Development of a 3D corneal epithelial model for early biocompatibility screening of topical ophthalmic formulations [PDF]

Iskra Davkova, Ivana Cvetkovikj Karanfilova, Ana Trajkovska, Veronika Stoilkovska Gjorgievska, Svetlana Kulevanova, Gjoshe Stefkov, Marija Karapandzova
Effects of temperature on THC and THCA content during storage [PDF]

Enkelejda Goci, Entela Haloci, Claudio Ferrante, Bleona Pasha
Allelopathy, Cardiotoxicity and Lethality bioassays of essential oils [PDF]

Hrisanta Godzo, Olga Gigopulu, Bobi Acevski, Frosina Dimoska, Marija Nuneva, Jelena Acevska, Ana Poceva Panovska, Katerina Brezovska
Application of ATR-FTIR as a screening method for analysis of biopharmaceutical preparations containing trastuzumab [PDF]

Gentiana Mehmeti, Nikola Geshkovski, Katerina Brezovska, Aneta Dimitrovska, Suzana Trajkovic Jolevska, Rumenka Petkovska, Jelena Acevska
Analytical strategy for discrimination between different origins of Metformin film-coated tablets [PDF]

Zoran Zhivikj, Lidija Petrushevska-Tozi, Nikola Geskovski, Kristina Shutevska, Ana Marija Bajatovska, Marija Karapandzova, Tatjana Kadifkova Panovska, Tanja Petreska Ivanovska
Evaluation of weight loss supplements toxicity in rifampicin pre-treated HepG2 cells [PDF]

Ana Marija Bajatovska, Zoran Zhivikj, Kristina Shutevska, Marija Karapandzova, Tanja Petreska Ivanovska, Lidija Petrushevska-Tozi, Tatjana Kadifkova Panovska
Toxicity screening of weight loss tea products by Brine Shrimp Lethality Assay [PDF]

Teodora Tasevska, Lina Livrinska, Ljubica Mihailova, Dushko Shalabalija, Nikola Geskovski, Marija Glavas Dodov, Katerina Goracinova, Kristina Mladenovska, Renata Slaveska Raichki, Maja Simonoska Crcarevska
Validation of method for rheological characterization of poloxamer 407 hydrogels used for 3D bioprinting [PDF]

Marjan Piponski, Irena Slaveska Spirevska, Tanja Bakovska Stoimenova, Kristina Grncharoska, Martina Miloshevska, Milena Prculovska, Marika Bogoevska, Stefan Stefov
Fast simple hplc method for determination of spironolactone related compounds [PDF]

Valentina Gocić, Ana Marković, Jelena Lazarević, Andrija Šmelcerović
Evaluation of DNase I inhibitory activity on synthetic halogenated chalcone derivatives [PDF]

Katarina Ilić, Jelena Zvezdanović, Jelena Lazarević
Synthesis and evaluation of lipid peroxidase inhibition of 4-methyl substituted coumarins [PDF]

Filip Djokoski, Marija Hiljadnikova-Bajro
The impact of the human microbiome on cancer immunotherapy [PDF]

Done Stojanov, Marija Glavas Dodov, Aleksandar Velinov, Martina Nestorovska
Principal Component Analysis to evaluate the stability impact of protein mutations: the case of SARS-CoV-2 K417T mutation [PDF]

Zorica Naumovska, Aleknsandra Kapedanovska Nestorovska, Maja Simonoska Crcarevska, Zoran Sterjev, Aleksandar Dimovski, Ljubica Shuturkova
Predictive model for determination of relative ABCB1 gene expression in different tissues [PDF]

Dushko Shalabalija, Ljubica Mihailova, Nikola Geskovski, Andreas Zimmer, Marija Glavas Dodov
Cytotoxic potential of nanoliposomes on hCMEC/D3 and SH-SY5Y cell lines [PDF]

Teodora Tasevska, Ivana Adamov, Nikola Geskovski, Maja Simonoska Crcarevska,Katerina Goracinova, Svetlana Ibrić
Digital light processing 3D printing of Hydrochlorothiazide with modified release [PDF]

Omer Yedikaya, Ulya Badilli, Gulin Amasya, Nurten Ozdemir
Design and optimization of a chitosan coated nanostructured lipid carriers of paliperidone [PDF]

Ranim Saker, Géza Regdon jr., Tamás Sovány
The application of carboxylic acids on the surface of titanate nanotubes for further functionalization [PDF]

Alharith A.A. Hassan, Katalin Kristó, Géza Regdon Jr., Viktória Varga, Edit Csapó, Tamás Sovány
Step by step preparation and optimization of lysozyme hydrophobic ion pairing complex [PDF]

Ivana Vasiljević, Paulina Pasik, Erna Turković, Branka Ivković, Arkadiusz Hejduk, Janina Lulek, Jelena Parojčić
The influence of directly compressible fillers/diluents on selected compact properties and drug dissolution – case study of rivaroxaban [PDF]

Erna Turković, Elena Velkoska, Ana Marija Nančeva, Ivana Vasiljević, Katerina Goračinova, Jelena Parojčić
An investigation into applicability of sodium carboxymethylcellulose and sodium alginate as film-forming agents for semi-solid 3D printing [PDF]

Sanja Dukovska, Elizabeta Atanaskova, Maja Simonoska Crcarevska, Marija Glavas Dodov, Katerina Goracinova, Nikola Geskovski
Suitability of Wurster-Fluid Bed technique for functional Eudragit L-100 coating on tablet cores [PDF]

Sara Ristevska, Hristina Litovin, Hrisanta Godzo, Teodora Tasevska, Lina Livrinska, Nikola Geskovski, Katerina Gorachinova, Kristina Mladenovska, Renata Slaveska Raichki, Marija Glavash Dodov, Maja Simonoska Crcarevska
Effect of surfactant stabilizers on physico-chemical properties of PLGA nanoparticles loaded with tetrahydrocannabinol [PDF]

Lina Livrinska, Teodora Tasevska, Dushko Shalablija, Ljubica Mihailova, Marija Glavash Dodov, Radmil Polenakovikj, Trajche Velkovski, Maja Simonoska Crcarevska
Effect of calcium chloride on physical properties of blended alginate carboxymethyl cellulose wound dressings [PDF]

Amina Tucak-Smajić, Ivana Ruseska, Edina Vranić, Andreas Zimmer
Functionalization of miRNA—cNLC complexes [PDF]

Ivana Ruseska, Amina Tucak-Smajić, Edina Vranić, Andreas Zimmer
Tracing the cellular uptake of nanostructured lipid carriers as delivery systems for miRNA [PDF]

Sila Turan, Gulin Amasya, Ozge Inal, Ulya Badilli
Pickering emulsions: Development of an all-in-one dermocosmetic formulation [PDF]

Ivana Stojanovska, Toshe Rafajlov, Beti Djurdjic, Lina Livrinska, Maja Simonoska Crcarevska, Katerina Goracinova, Selestina Gorgieva, Vineta Vuksanovich , Nikola Geskovski
Screening the effects of process and formulation factors upon the physical properties of Chitosan-TPP nanoparticles as drug delivery carriers for Gentamycin sulphate [PDF]

Volume 64 (2)

Volume 64 (2)

Katerina Cvetkovska, Biljana Bauer
Ethnopharmacological and toxicological review of Cydonia oblonga M. [PDF]
Early on-line 07 March 2019

Svetlana Cekovska, Sasho Stoleski S, Violeta Soleva, Katerina Tosheska-Trajkovska, Danica Labudovik, Jasna Bogdanska , Julijana Brezovska-Kavrakova, Irena Kostovska, Biljana Bauer, Sonja Topuzovska
Enzymatic changes in orchard workers with occupational exposure to pesticides [PDF]
Early on-line 07 March 2019

Emilija Janeva, Liljana Anastasova, Irena Slaveska Spirevska, Tatjana Rusevska, Tanja Bakovska Stoimenova, Teuta Ibrahimi, Rumenka Petkovska
A comparative in vitro dissolution study of generic moxifloxacin immediate-release film coated tablets and referent pharmaceutical product [PDF]
Early on-line 07 March 2019

Selvete Shuleta-Qehaja, Aleksandra Kapedanovska Nestorovska, Zorica Naumovska, Petar Stefanovski, Aleksandar J Dimovski, Zoran Sterjev, Ljubica Shuturkova
CYP2D6 polymorphisms and the therapeutic outcome with Tamoxifen therapy in breast cancer patients from Kosovo [PDF]
Early on-line 07 March 2019

Tanturovski Zharko, Zorica Arsova-Sarafinovska, Aneta Dimitrovska
RP-HPLC method with indirect UV detection for determination of sodium ibandronate in pharmaceuticals [PDF]
Early on-line 07 March 2019

Marina Todorovska Ackovska, Nikola Geskovski, Katerina Goracinova
Determination of significant factors in high-shear granulation process of sucrose with aqueous solution of sodium lauryl sulphate using partial least square regression approach [PDF]
Early on-line 26 March 2019

Elena Kazandjievska, Iva Antova, Slavica Mitrevska, Aleksandar Dimkovski, Elena Dimov, Maja Hadzieva Gigovska, Packa Antovska, Sonja Ugarkovic, Jasmina Tonic Ribarska, Suzana Trajkovic-Jolevska
Non-compendial vs compendial analytical tests – a powerful tool for predicting in vitro similarity of highly viscous oral suspension [PDF]
Early on-line 26 March 2019

Liljana Anastasova, Tanja Petreska Ivanovska, Rumenka Petkovska, Lidija Petrusevska-Tozi
Concepts, benefits and perspectives of functional dairy food products [PDF]
Early on-line 26 March 2019

Volume 64 (1)

Volume 64 (1)

Andzela Brajanovska, Biljana Bauer
Helleborus sp. an ethnopharmacological and toxicological review [PDF]

Milena Dobrkovikj Shotarovska, Hristina Babunovska, Aneta Dimitrovska
Data integrity aspects of reporting results for the specification parameter related and degradation products in chromatography data system [PDF]

Maja Hadzieva Gigovska, Ana Petkovska, Blagica Manchevska, Jelena Acevska, Natalija Nakov, Packa Antovska, Sonja Ugarkovic, Aneta Dimitrovska
Chemometrically assisted optimization, development and validation of UPLC method for the analysis of simvastatin [PDF]

Mena Ivanoska, Hristina Babunovska, Rumenka Petkovska
Functional risk assessment as part of the validation in the implementation of chromatography data system [PDF]

Aleksandra Kapedanovska Nestorovska, Zorica Naumovska, Krume Jakovski, Zoran Sterjev, Nadica Matevska Geskovska, Aleksandar Dimovski, Ljubica Suturkova
Allele frequency and genotype distribution of aldo keto reductase 1D1 (AKR1D1) rs1872930 genetic variant in a Macedonian population [PDF]

Arijeta Shabani, Marija Karapandzova, Ivana Cvetkovikj Karanfilova, Gjoshe Stefkov, Svetlana Kulevanova
GC-MS analysis of the essential oil, aroma components and n-hexane extract of St. John Wort (Hypericum perforatum L., Hypericaceae) [PDF]

Biljana Lazarova, Aleksandra Kapedanovska Nestorovska, Zoran Sterjev, Ljubica Suturkova
Cost-effectiveness of LMWHs versus UFH for the prevention of postsurgical venous thromboembolism at orthopedic department in Clinical Hospital Stip [PDF]

Marina Kacarska, Julija Zivadinovic
Root anatomy and apical canal morphology of maxillary first premolars [PDF]

Volume 64

Volume 63

Volume 63 (1)

Volume 63 (1)

Dimce Dzingarski, Kristina Mladenovska
Pharmacotherapy in chronic kidney disease hyperphosphatemia – effects on vascular calcification and bone health [PDF]

Biljana Lazarova, Aleksandra Kapedanovska Nestorovska, Zoran Sterjev, Ljubica Suturkova
Evaluation of costs and outcomes associated with pharmacological thromboprophylaxis (unfractionated heparin and low molecular weight heparins) of venous thromboembolism at orthopedic ward in Clinical Hospital Stip [PDF]

Nikola Gigovski, Vesna Korunoska Stevkovska, Aneta Mijoska, Sanja Pancevska, Emilija Valjakova Bajraktarova, Ana Gigovska Arsova
Time-depending solubility of different fixed prosthetic permanent luting cements [PDF]

Ana Sotirovska Ivkovska, Efka Zabokova-Bilbilova, Zlatko Georgiev, Emilija Bajraktarova Valjakova, Ljube Ivkovski
Innate immune response of the dental pulp in healthy and carious human teeth [PDF]

Irina Mladenoska, Verica Petkova, Tatjana Kadifkova Panovska
Pre-fermentative treatment of a model wine with aim to serve as a functional food with decreased alcohol content [PDF]

Borjan Naumovski, Jadranka Bundevska, Biljana Kapusevska
Comparison of double-phase impression technique in 1 step and 2 steps by evaluating dimensional stability and accuracy of condensation silicones [PDF]

Efka Zabokova Bilbilova, Ana Sotirovska Ivkovska, Olivera Sarakinova, Olga Kokoceva Ivanovska, Natasha Stavreva
Correlation between pH, buffering capacity, calcium and dental caries in schoolchildren [PDF]

Katerina V. Geshoska, Jagoda Bajevska
Effect of manufacturing protocol on the internal fit and marginal discrepancy of metal ceramic and full ceramic dental crowns [PDF]

Volume 62

Volume 62 (2)

Volume 62 (2)
Available on-line 03 November 2017.

Full Issue [PDF] [Cover Page]

Nadica Sibinovska, Venera Komoni, Katerina Ancevska Netkovska, Edina Vranic, Maja Simonoska Crcarevska, Marija Glavas Dodov
Novel approaches in treatment of Acne vulgaris: Patents related to micro/nanoparticulated carrier systems [PDF]

Elias Adikwu, Brambaifa Nelson, Wolfe Atuboyedia Obianime
Melatonin and alpha lipoic acid attenuate lopinavir/ritonavir induced-testicular toxicity in albino rats [PDF]

Vjollca Qerimi, Aleksandra Kapedanovska Nestorovska, Zoran Sterjev, Sonja Genadieva-Stavric, Ljubica Suturkova
Overview of cost-effectiveness analysis and health state utilities in multiple myeloma and estimations of health state utilities from real-world macedonian data [PDF]

Vladimir Rendevski, Boris Aleksovski, Milena Kolevska, Dragan Stojanov, Koco Dimitrovski, Ana Mihajlovska Rendevska, Vasko Aleksovski, Aleksandar Petlickovski, Dejan Trajkov, Kiro Stojanoski
Effects of data transformation on multivariate analyses in intracerebral hemorrhage [PDF]

Zoran Arsovski, Dejan Dokic, Zlatica Gosheva, Elena J. Janeva, Anita Arsovska, Viktor Isjanovski
Altered therapeutic response towards inhaled corticosteroids in asthmatics–smokers with mild asthma [PDF]

Sotirija Duvlis, Marija Hiljadnikova Bajro, Dijana Plaseska Karanfilska
Association of p53Pro72Arg (rs1042522) and MDM2309 (rs2279744) polymorphisms with risk for cervical intraepthelial lesions and cervical cancer development in Macedonian women [PDF]

Zoran Arsovski, Gorica Breshkovska, Dejan Dokic, Elena Ј. Janeva, Anita Arsovska, Viktor Isjanovski
The influence of inhaled corticosteroids on asthma control test in smokers and non-smokers with asthma [PDF]

Elizabeta Zisovska, Blerina Koshi, Renata Slaveska-Raichki
A study of off-label and unlicensed medicines use in Macedonian neonatal units [PDF]